Ten-year-old Auggie Pullman, who was born with extreme facial abnormalities and was not expected to survive, goes from being home-schooled to entering fifth grade at a private middle school in Manhattan, which entails enduring the taunting and fear of his classmates as he struggles to be seen as just another student

Second-grader Lola has a wonderful family, a great teacher, and the best friend ever, Josh, and they all help her feel better after she is teased and forbidden to play team sports at recess for having accidentally hurt classmate Juan during a soccer game.

Otis is very angry when his best friend is teased by his schoolmates, but their teacher intervenes and introduces activities that affirm the importance of every student in the class while teaching that teasing is harmful.